UK-432097, CAS 380221-63-6

Product Description: UK-432097 is a highly potent and selective A2AAR agonist with a pKi of 8.4 for human A2AAR. UK-432097 has anti-inflammatory and anti-aggregatory properties. UK-432097 has the potential for COPD (Chronic Obstructive Pulmonary Disease) research[1][2][3].

Applications: COVID-19-immunoregulation

Formula: C40H47N11O6

References: [1]Fei Xu, et al. Structure of an agonist-bound human A2A adenosine receptor. Science. 2011 Apr 15;332(6027):322-7./[2]Kenneth A Jacobson, et al. Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development. Front Cell Neurosci. 2019 Mar 28;13:124./[3]J Daniel Hothersall, et al. Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics. Mol Pharmacol. 2017 Jan;91(1):25-38.

CAS Number: 380221-63-6

Molecular Weight: 777.87

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Adenosine Receptor

• SKU: MEXHY-107046-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-107046-5
• Package Unit: 5 mg
• Quantity Unit: STK