Umeclidinium (bromide), CAS 869113-09-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-(hydroxydiphenylmethyl)-1-[2-(phenylmethoxy)ethyl]-1-azoniabicyclo[2.2.2]octane, monobromide

Purity: ≥98%

Formula Markup: C29H34NO2 / Br

Formula Weight: 508.5

CAS Number: 869113-09-7

Notes: Umeclidinium is an antagonist of muscarinic acetylcholine receptors (Kis = 0.05-0.16 nM for M1-M5 human recombinant receptors).{39900,39902} It inhibits acetylcholine-induced activation of recombinant M3 receptors in CHO cell membranes (IC50 = 50 = 10 µM) and bronchoconstriction in mice when administered intranasally (ED50 = 0.02 µg).{39900,39901} Formulations containing umeclidinium have been used in the treatment of chronic obstructive pulmonary disease (COPD).

• SKU: CAY20700-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 20700-50
• Package Unit: 50 mg
• Quantity Unit: STK