Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 6-bromo-4-[((dimethyl-d3)amino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic acid, ethyl ester, monohydrochloride
Purity: ≥99% deuterated forms (d1-d6)
Formula Markup: C22H19D6BrN2O3S / HCl
Formula Weight: 519.91258
CAS Number: 2928218-29-3
Notes: Umifenovir-d6 is intended for use as an internal standard for the quantification of umifenovir (Item No. 16933) by GC- or LC-MS. Umifenovir is a broad-spectrum antiviral agent.{27500} It inhibits the replication of H5N1 influenza (IC50 = 30 µg/ml) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro (IC50 = 3.537 µM).{27500,60151} Umifenovir inhibits entry of hepatitis C virus (HCV) pseudoparticles in Huh7 cells (IC50 = 6 µg/ml) and inhibits Zika virus protein synthesis in Vero cells.{27500,60152} In vivo, umifenovir (45 mg/kg) reduces the formation of influenza-induced lung lesions in ferrets.{60153}
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