Product Description: UNBS5162 is a pan-antagonist of CXCL chemokine expression, with anti-tumor activity.
Applications: Cancer-Kinase/protease
Formula: C17H18N4O3
References: [1]Mijatovic T, et al. UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers. Neoplasia. 2008 Jun;10(6):573-86./[2]Tina Mahieu, et al. UNBS5162: A novel naphthalimide derivative with potent pro-autophagic effects in human cancer cells. Cancer Research, 2007 May; 67(9) Supplement./[3]He D, et al. UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway. Mol Med Rep. 2018 Jan;17(1):549-555.
CAS Number: 956590-23-1
Molecular Weight: 326.35
Compound Purity: 99.92
Research Area: Cancer; Endocrinology
Solubility: DMSO : 21.5 mg/mL (ultrasonic;warming)
Target: Autophagy;CXCR
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