UNC2250, CAS 1493694-70-4

Product Description: UNC2250 is a potent and selective Mer inhibitor with an IC50 of 1.7 nM, about 160- and 60-fold selectivity over the closely related kinases Axl/Tyro3.

Applications: Cancer-Kinase/protease

Formula: C24H36N6O2

References: [1]Zhang, W., et al., Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors. J Med Chem, 2013. 56(23): p. 9683-92./[2]Xiaodong Wang, et al. Pyrimidine compounds for the treatment of cancer.WO2013177168A1.

CAS Number: 1493694-70-4

Molecular Weight: 440.58

Compound Purity: 99.92

Research Area: Cancer

Solubility: 0.1 M HCL : 12.5 mg/mL (ultrasonic;adjust pH to 3 with HCl)/DMSO : ≥ 10 mg/mL

Target: TAM Receptor

• SKU: MEXHY-15797-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15797-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK