UPGL00004, CAS 1890169-95-5

Product Description: UPGL00004 is a potent allosteric glutaminase C (GAC) inhibitor (IC50=29 nM; Kd=27 nM). UPGL00004 strongly inhibits the proliferation of highly aggressive triple-negative breast cancer cell lines[1].

Applications: Cancer-programmed cell death

Formula: C25H26N8O2S2

References: [1]Huang Q, et al. Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism. J Biol Chem. 2018 Mar 9;293(10):3535-3545.

CAS Number: 1890169-95-5

Molecular Weight: 534.66

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Glutaminase

• SKU: MEXHY-119377-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-119377-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK