Uprosertib, CAS 1047634-65-0

Product Description: Uprosertib (GSK2141795) is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively.

Applications: Cancer-Kinase/protease

Formula: C18H16Cl2F2N4O2

References: [1]Pachl F, et al. Characterization of a chemical affinity probe targeting Akt kinases. J Proteome Res. 2013 Aug 2;12(8):3792-800./[2]Jacobsen K, et al. Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer. Nat Commun. 2017 Sep 4;8(1):410.

CAS Number: 1047634-65-0

Molecular Weight: 429.25

Compound Purity: 99.74

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Akt

• SKU: MEXHY-15965-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15965-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK