Description: Uprosertib (GSK2141795) (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.
CAS Number: 1047634-65-0
Formula: C18H16Cl2F2N4O2
Molecular Weight: 429,25
References: Pachl F, et al. J Proteome Res. 2013, 12(8), 3792-3800.