Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate
Purity: ≥98%
Formula Markup: C20H22N2O3
Formula Weight: 338.4
CAS Number: 546141-08-6
Notes: URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH), the enzyme that hydrolyzes anandamide (AEA; Item No. 90050) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and intact neurons, respectively).{10666,3310} URB597 exhibits both antinociceptive and anxiolytic effects in vivo without evoking other symptoms associated with cannabinoid-like compounds. This antinociceptive effect is similar to those observed in FAAH(-/-) mice.{9576}