Vadadustat, CAS 1000025-07-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[[5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]-glycine

Purity: ≥98%

Formula Markup: C14H11ClN2O4

Formula Weight: 306.70092

CAS Number: 1000025-07-9

Notes: Vadadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and HIF-PH3 (IC50s = 1.1 and 0.39 micromolar, respectively).{51165} It stabilizes HIF-1α in mouse hepatocyte nuclear extracts. Vadadustat (50 and 100 mg/kg) increases erythropoietin levels in mouse serum.

• SKU: CAY15295-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 15295-10
• Package Unit: 10 mg
• Quantity Unit: STK