Valbenazine, CAS 1025504-45-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: L-valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester

Purity: ≥98%

Formula Markup: C24H38N2O4

Formula Weight: 418.5696

CAS Number: 1025504-45-3

Notes: Valbenazine is an inhibitor of vesicular monoamine transporter 2 (VMAT2; Kis = 110 and 150 nM in rat striatum homogenates and human platelets, respectively).{47247} It is selective for VMAT2 over a panel of 80 receptors, transporters, and ion channels, including the serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, and 5-HT2B and dopamine D1 and D2 receptors. Valbenazine induces ptosis in rats, indicating norepinephrine depletion. Formulations containing valbenazine have been used in the treatment of tardive dyskinesia.

• SKU: CAY26809-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 26809-25
• Package Unit: 25 mg
• Quantity Unit: STK