Varlitinib, CAS 845272-21-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N4-[3-chloro-4-(2-thiazolylmethoxy)phenyl]-N6-[(4R)-4,5-dihydro-4-methyl-2-oxazolyl]-4,6-quinazolinediamine

Purity: ≥98%

Formula Markup: C22H19ClN6O2S

Formula Weight: 466.9442

CAS Number: 845272-21-1

Notes: Varlitinib is an inhibitor of EGFR and HER2 (IC50s = 7 and 2 nM, respectively).{48649,48650} It inhibits cell proliferation (IC50s = In vivo, varlitinib (100 mg/kg) inhibits phosphorylation of EGFR and ERK and reduces tumor weight in an MDA-MB-468 mouse xenograft model.

• SKU: CAY27651-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27651-5
• Package Unit: 5 mg
• Quantity Unit: STK