Vatalanib (succinate), CAS 212142-18-2

Product Description: Vatalanib (PTK787) succinate is a potent and orally active VEGFR inhibitor with IC50s of 37 nM, 77 nM, 270 nM, 660 nM, 730 nM, 1400 nM, and 580 nM for KDR, Flt-1, Flk, Flt-4, c-Kit, c-Fms, and PDGFR-β, respectively[1].

Applications: Cancer-Kinase/protease

Formula: C24H21ClN4O4

References: [1]J M Wood, et al. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res. 2000 Apr 15;60(8):2178-89.

CAS Number: 212142-18-2

Molecular Weight: 464.90

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: VEGFR

• SKU: MEXHY-110272-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-110272-25
• Package Unit: 25 mg
• Quantity Unit: STK