VEGF-CC, Human (116a.a, HEK293)

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Product Description: VEGF-C Protein, Human (116a.a, HEK293) functions in lymphangiogenesis, where it acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3 promoting survival, growth and migration.

Formula: 7424(Gene_ID)P49767 (A112-R227)(Accession)

References: [1]Joukov V, et al. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J. 1996 Jan 15;15(2):290-98./[2]Tammela T, et al. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation Nature. 2008 Jul 31;454(7204):656-60./[3]Le Bras B, et al. VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci. 2006 Mar;9(3):340-8./[4]Machnik A, et al. Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med. 2009 May;15(5):545-52.

Molecular Weight: Approximately 15-24 kDa due to the glycosylation.

Compound Purity: 95.00

• SKU: MEXHY-P7313-500UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P7313-500UG
• Package Unit: 500 μg
• Quantity Unit: STK