VEGFR-2-IN-44, CAS 288144-20-7

Product Description: VEGFR-2-IN-44 (compound 4b) is a selective VEGF-R2 (Flk-1) inhibitor with an IC50 value of 70 nM. VEGFR-2-IN-44 also inhibits PDGF-Rβ with an IC50 of 920 nM[1].

Applications: Cancer-Kinase/protease

Formula: C17H15BrN2O

References: [1]L Sun, et al. Identification of substituted 3-[(4,5,6, 7-tetrahydro-1H-indol-2-yl)methylene]-1,3-dihydroindol-2-ones as growth factor receptor inhibitors for VEGF-R2 (Flk-1/KDR), FGF-R1, and PDGF-Rbeta tyrosine kinases. J Med Chem. 2000 Jul 13;43(14):2655-63.

CAS Number: 288144-20-7

Molecular Weight: 343.22

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PDGFR;VEGFR

• SKU: MEXHY-112337-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112337-1
• Package Unit: 1 mg
• Quantity Unit: STK