Vilagletistat, CAS 1542132-88-6

Product Description: ZED-1227 is a specific and orally active transglutaminase 2 (TG2) inhibitor, with an IC50 of 45 nM. ZED-1227 can block inflammation-induced TG2 expression and activity. ZED-1227 can be used for the research of celiac disease (CeD)[1][2].

Applications: COVID-19-immunoregulation

Formula: C26H36N6O6

References: [1]Manu Encalada, et al. The Oral Transglutaminase 2 (TG2) Inhibitor Zed1227 Blocks TG2 Activity in a Mouse Model of Intestinal Inflammation. Gastroenterology. 154(6):S-490./[2]Christian Büchold, et al. Pyridinone derivatives as tissue transglutaminase inhibitors. WO2014012858A1.

CAS Number: 1542132-88-6

Molecular Weight: 528.60

Compound Purity: 99.97

Research Area: Inflammation/Immunology

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Glutaminase

• SKU: MEXHY-19359-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19359-25
• Package Unit: 25 mg
• Quantity Unit: STK