Product Description: Vilazodone (EMD 68843; SB 659746A) is a potent, selective and orally active?serotonin?reuptake inhibitor (SSRI) and partial?5-HT1A receptor agonist. Vilazodone exhibits antidepressant efficacy in vivo can be used for the research of major depressive disorder (MDD) and affective disorders[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C26H27N5O2
Citations: Arch Pharm (Weinheim). 2024 May 30:e2400263./Nature. 2023 Dec;624(7992):672-681./Prog Neuropsychopharmacol Biol Psychiatry. 2023 Dec 6:110911./Mol Pharmacol. 2023 Nov;104(5):230-238.
References: [1]Lee A. Dawson et al. Vilazodone: A 5-HT1A Receptor Agonist/Serotonin Transporter Inhibitor for the Treatment of Affective Disorders CNS Neuroscience & Therapeutics Volume 15, Issue 2, pages 107-117, June 2009/[2]Cruz MP. Vilazodone HCl (Viibryd): A Serotonin Partial Agonist and Reuptake Inhibitor For the Treatment of Major Depressive Disorder. P T. 2012 Jan;37(1):28-31.
CAS Number: 163521-12-8
Molecular Weight: 441.52
Compound Purity: 99.84
Research Area: Neurological Disease
Solubility: DMSO : 75 mg/mL (ultrasonic)
Target: 5-HT Receptor;Serotonin Transporter