Vimentin (Mesenchymal Cell Marker)(VIM/3736), CF740 conjugate, 0.1mg/mL

Vimentin (Mesenchymal Cell Marker)(VIM/3736), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC743736-100
Packaging Unit
100 uL
Manufacturer
Biotium

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Description: This MAb reacts with a 58 kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP s) such as desmin, keratin, neurofilament, and glial fibrillary acid protein. Anti-vimentin alone is of limited value as a diagnostic tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e. g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: VIM/3736

Immunogen: A recombinant fragment (around aa 2-466) of human Vimentin protein (exact sequence is proprietary)

Antibody Reactivity: Vimentin

Entrez Gene ID: 7431

Z-Antibody Applications: IHC, FFPE (verified)/WB (verified)

Verified AB Applications: IHC (FFPE) (verified)/WB (verified)
More Information
SKU BTMBNC743736-100
Manufacturer Biotium
Manufacturer SKU BNC743736-100
Package Unit 100 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Western Blotting, Immunohistochemistry
Isotype IgG2b kappa
Host Mouse
Conjugate Conjugated, CF740
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