Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 3Z-[2E-[(1R,3aS,7aR)-1S-[1R,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexanol
Purity: ≥98%
Formula Markup: C27H44O
Formula Weight: 384.6
CAS Number: 67-97-0
Notes: Vitamin D3 is a biologically inactive precursor to calcitriol (Item No. 71820) that is converted to active metabolites in vivo.{23284,15096} Vitamin D3 is obtained from dietary sources, including fish, or formed in the epidermis via photolytic conversion of 7-dehydro cholesterol (Item No. 14612) to previtamin D3 by UVB radiation, followed by isomerization to vitamin D3.{19039,23286} Vitamin D3 can then be converted to 25-hydroxy vitamin D3 (Item No. 9000683) in the liver by the cytochrome P450 (CYP) isoform CYP2R1 before being converted to calcitriol by CYP27B1 in the kidney.{15096,19039} Formulations containing vitamin D3 have been used in the treatment of osteoporosis.
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