Application Note: IHC-P: 3-6μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89450-PEP).
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Uniprot ID: Q9H270
Antigen Species: Human
Immunogen: Peptide with sequence C-HALQEKDTQTKLE, from the internal region of the protein sequence according to NP_068375.3.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: VPS11 core subunit of CORVET and HOPS complexes
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