Product Description: VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM. VU 0255035 reduces pilocarpine-induced seizures in mice. VU0255035 is used to examine the role of the M1 receptor in diverse situations[1].
Applications: Neuroscience-Neuromodulation
Formula: C18H20N6O3S2
References: [1]Sheffler DJ, et al. A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning. Mol Pharmacol. 2009 Aug;76(2):356-68.
CAS Number: 1135243-19-4
Molecular Weight: 432.52
Compound Purity: 99.76
Research Area: Neurological Disease
Solubility: DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)