VU0420373, CAS 38376-29-3

Product Description: VU0420373 is a potent heme sensor system (HssRS) activator with an EC50 of 10.7 μM and a pEC50 of 4.97. VU0420373 induces heme biosynthesis, and is toxic to fermenting S. aureus[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C15H11FN2O

References: [1]Brendan F Dutter, et al. Decoupling Activation of Heme Biosynthesis From Anaerobic Toxicity in a Molecule Active in Staphylococcus Aureus. ACS Chem Biol. 2016 May 20;11(5):1354-61.

CAS Number: 38376-29-3

Molecular Weight: 254.26

Compound Purity: 99.99

Research Area: Infection; Metabolic Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Bacterial

• SKU: MEXHY-115658-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-115658-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK