VU0463271, CAS 1391737-01-1

Product Description: VU0463271 is a selective KCC2 antagonist, with an IC50 of 61 nM.

Applications: Neuroscience-Neuromodulation

Formula: C19H18N4OS2

References: [1]Delpire E, et al. Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: development of a highly selective and more potent in vitro probe. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4532-5./[2]Rui Chen, et al. Functional Coupling of K +-Cl - Cotransporter (KCC) to GABA-Gated Cl - Channels in the Central Nervous System of Drosophila melanogaster Leads to Altered Drug Sensitivities. ACS Chem Neurosci. 2019 Jun 19;10(6):2765-2776.

CAS Number: 1391737-01-1

Molecular Weight: 382.50

Compound Purity: 99.67

Research Area: Neurological Disease

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Potassium Channel

• SKU: MEXHY-110110-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-110110-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK