VU591, CAS 1222810-74-3

Product Description: VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 can be used for neurological research with HY-108585 (the equivalent of VU591 hydrochloride)[1].

Formula: C16H12N6O5

References: [1]Bhave G, et al. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol Pharmacol. 2011 Jan;79(1):42-50./[2]Masayoshi Okada, et al. Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ. PLoS One. 2020 Nov 13;15(11):e0233815.

CAS Number: 1222810-74-3

Molecular Weight: 368.30

Compound Purity: 98.39

Research Area: Neurological Disease

Solubility: DMSO : 62.5 mg/mL (ultrasonic)

Target: Potassium Channel

• SKU: MEXHY-108585A-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108585A-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK