VU6005649, CAS 2137047-43-7

Product Description: VU6005649 is a CNS penetrant mGlu7/8 receptor agonist with EC50s of 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively.

Applications: Neuroscience-Neuromodulation

Formula: C16H12F5N3O

References: [1]Abe M, et al. Discovery of VU6005649, a CNS Penetrant mGlu7/8 Receptor PAM Derived from a Series of Pyrazolo[1,5-a]pyrimidines. ACS Med Chem Lett. 2017 Sep 1;8(10):1110-1115.

CAS Number: 2137047-43-7

Molecular Weight: 357.28

Compound Purity: 99.53

Research Area: Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: mGluR

• SKU: MEXHY-107982-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-107982-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK