VUF11207 (fumarate), CAS 1785665-61-3

Product Description: VUF11207 fumarate is a CXCR7 agonist that binds specifically to CXCR7. VUF11207 fumarate reduces CXCL12-mediated osteoclastogenesis and bone resorption by inhibiting ERK phosphorylation[1].

Applications: Cancer-programmed cell death

Formula: C31H39FN2O8

References: [1]Wijtmans M, et al. Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists. Eur J Med Chem. 2012 May;51:184-92./[2]Nugraha AP, et al. C‑X‑C receptor 7 agonist acts as a C‑X‑C motif chemokine ligand 12 inhibitor to ameliorate osteoclastogenesis and bone resorption. Mol Med Rep. 2022 Mar;25(3):78.

CAS Number: 1785665-61-3

Molecular Weight: 586.65

Compound Purity: 98.50

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: CXCR

• SKU: MEXHY-110318-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-110318-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK