WEHI-345, CAS 1354825-58-3

Product Description: WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation[1].

Applications: Cancer-Kinase/protease

Formula: C22H23N7O

References: [1]Nachbur U, et al. A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production. Nat Commun. 2015 Mar 17;6:6442.

CAS Number: 1354825-58-3

Molecular Weight: 401.46

Compound Purity: 99.31

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: RIP kinase

• SKU: MEXHY-18937-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18937-50
• Package Unit: 50 mg
• Quantity Unit: STK