WHI-P154, CAS 211555-04-3

Product Description: WHI-P154 is a potent EGFR inhibitor, and also modestly blocks JAK3, with IC50s of 4 nM and 1.8 μM, respectively.

Applications: Cancer-Kinase/protease

Formula: C16H14BrN3O3

References: [1]Changelian PS, et al. The specificity of JAK3 kinase inhibitors. Blood. 2008 Feb 15;111(4):2155-7. Epub 2007 Dec 19./[2]Zhang H, et al. WHI-P154 enhances the chemotherapeutic effect of anticancer agents in ABCG2-overexpressing cells. Cancer Sci. 2014 Aug;105(8):1071-8.

CAS Number: 211555-04-3

Molecular Weight: 376.20

Compound Purity: 99.39

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Apoptosis;EGFR;JAK

• SKU: MEXHY-13895-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13895-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK