Shelf life (days): 730.0
Formulation: A crystalline solid
Formal Name: 6a,7a-epoxy-5a,20,22R-trihydroxy-1-oxo-ergosta-2,24-dien-26-oic acid d-lactone
Purity: ≥95%
Formula Markup: C28H38O6
Formula Weight: 470.6
CAS Number: 32911-62-9
Notes: Withanolide A is a natural product isolated from the medicinal plant W. somnifera that has antioxidant and neuroprotective activity.{28425} It helps to promote neurite outgrowth at 1 µM in cultured neurons and in rodents injected with Aβ(25-35), and also recovers Aβ(25-35)-induced memory deficit in mice (10 µmol/kg/day).{28426,28427} Withanolide A reverses hypoxia-mediated neurodegeneration by restoring hypoxia-induced glutathione depletion in the hippocampus of mice.{28428}