Wnt Agonist I, CAS 853220-52-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine

Purity: ≥98%

Formula Markup: C19H18N4O3

Formula Weight: 350.4

CAS Number: 853220-52-7

Notes: Wnt Agonist I is a cell-permeable activator of Wnt signaling that does not inhibit GSK3β (IC50 > 60 µM).{32213} It induces nuclear accumulation of β-catenin, increasing transcriptional activity driven by TCF (EC50 = 700 nM) and altering embryonic development.{32213,32212} Wnt Agonist I is effective in vivo, decreasing tissue damage and improving renal function after ischemia-reperfusion in rats.{32211}

• SKU: CAY19903-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19903-10
• Package Unit: 10 mg
• Quantity Unit: STK