WT-161, CAS 1206731-57-8

Product Description: WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM[1]. WT-161 also inhibits metallo-β-lactamase domain-containing protein?2 (MBLAC2)[2].

Applications: Cancer-programmed cell death

Formula: C27H30N4O3

References: [1]Hideshima T, et al. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13162-13167./[2]Severin Lechner, et al. Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target. Nat Chem Biol. 2022 Apr 28.

CAS Number: 1206731-57-8

Molecular Weight: 458.55

Compound Purity: 98.36

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: Apoptosis;Beta-lactamase;HDAC

• SKU: MEXHY-100871-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100871-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK