WZ4003, CAS 1214265-58-3

Product Description: WZ4003 is the first potent and highly specific NUAK kinase inhibitor with IC50 of 20 nM/100 nM for NUAK1 (ARK5)/NUAK2, without significant inhibition on other 139 kinases.

Applications: Cancer-Kinase/protease

Formula: C25H29ClN6O3

References: [1]Banerjee S, et al. Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. Biochem J. 2014 Jan 1;457(1):215-25./[2]Zhou W, et al. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M. Nature. 2009 Dec 24;462(7276):1070-4

CAS Number: 1214265-58-3

Molecular Weight: 496.99

Compound Purity: 98.03

Research Area: Cancer

Solubility: DMSO : 33.33 mg/mL (ultrasonic)

Target: AMPK

• SKU: MEXHY-15802-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15802-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK