XAP044, CAS 196928-50-4

Product Description: XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms[1].

Applications: Neuroscience-Neuromodulation

Formula: C15H9IO4

References: [1]Gee CE, et al. Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior. J Biol Chem. 2014;289(16):10975-10987.

CAS Number: 196928-50-4

Molecular Weight: 380.13

Compound Purity: 99.99

Research Area: Neurological Disease

Solubility: DMSO : ≥ 50 mg/mL

Target: mGluR

• SKU: MEXHY-110146-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-110146-5
• Package Unit: 5 mg
• Quantity Unit: STK