XEN445, CAS 1515856-92-4

Product Description: XEN445 is an endothelial lipase (EL) inhibitor with an IC50 of 0.237 uM. It has excellent ADME and PK activity and can increase the concentration of high-density lipoprotein cholesterol in mouse plasma.

Applications: COVID-19-immunoregulation

Formula: C18H17F3N2O3

References: [1]Sun S, et al. Discovery of XEN445: a potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice. Bioorg Med Chem. 2013 Dec 15;21(24):7724-34.

CAS Number: 1515856-92-4

Molecular Weight: 366.33

Compound Purity: 99.85

Research Area: Cardiovascular Disease

Solubility: DMSO : ≥ 40 mg/mL

Target: Others

• SKU: MEXHY-12246-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12246-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK