XL-281, CAS 870603-16-0

Product Description: XL-281 (BMS-908662) is an orally active inhibitor for RAF kinase, with IC50s of 2.6, 4.5 and 6 nM, for CRAF, B-RAF, and B-RAFV600E, respectively. XL-281 exhibits antitumor activity[1].

Applications: Cancer-Kinase/protease

Formula: C24H19ClN4O4

References: [1]Dickson MA, et al., Phase I study of XL281 (BMS-908662), a potent oral RAF kinase inhibitor, in patients with advanced solid tumors. Invest New Drugs. 2015 Apr;33(2):349-56.

CAS Number: 870603-16-0

Molecular Weight: 462.89

Research Area: Cancer

Target: Raf

• SKU: MEXHY-19343-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19343-10
• Package Unit: 10 mg
• Quantity Unit: STK