XL228, CAS 898280-07-4

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N4-(5-cyclopropyl-1H-pyrazol-3-yl)-N2-[[3-(1-methylethyl)-5-isoxazolyl]methyl]-6-(4-methyl-1-piperazinyl)-2,4-pyrimidinediamine

Purity: ≥98%

Formula Markup: C22H31N9O

Formula Weight: 437.5

CAS Number: 898280-07-4

Notes: XL228 is a tyrosine kinase inhibitor.{33640,33639} It inhibits the receptor tyrosine kinases insulin-like growth factor 1 receptor (IGF-1R) and FGFR2 (IC50s = 1.6 and 50s = 5, 3.1, 2, and 6.1 nM, respectively). XL228 inhibits proliferation of chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL) cell lines (IC50s = <100 nM).{60320}

• SKU: CAY21506-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21506-10
• Package Unit: 10 mg
• Quantity Unit: STK