Y16, CAS 429653-73-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-[[3-[(3-methylphenyl)methoxy]phenyl]methylene]-1-phenyl-3,5-pyrazolidinedione

Purity: ≥98%

Formula Markup: C24H20N2O3

Formula Weight: 384.42728

CAS Number: 429653-73-6

Notes: An inhibitor of the Rho GEF 12-RhoA protein-protein interaction; binds to the DH-PH domain of Rho GEF 12 in a cell-free assay (Kd = 76 nM); inhibits serum-induced phosphorylation of MLC and FAK, a marker of RhoA activity, in NIH3T3 cells at 10 and 30 µM; inhibits cell growth, migration, invasion, and mammosphere formation in MCF-7 breast cancer cells from 5-30 µM

• SKU: CAY42399-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42399-10
• Package Unit: 10 mg
• Quantity Unit: STK