Product Description: YK-3-237, a SIRT1 activator, targets mutant p53. YK-3-237 inhibits the proliferation of triple-negative breast cancer cells[1].
Applications: Cancer-programmed cell death
Formula: C19H21BO7
References: [1]Yong Weon Yi, et al. Targeting mutant p53 by a SIRT1 activator YK-3-237 inhibits the proliferation of triple-negative breast cancer cells. Oncotarget. 2013 Jul;4(7):984-94./[2]Murugavel Ponnusamy, et al. Activation of Sirtuin-1 Promotes Renal Fibroblast Activation and Aggravates Renal Fibrogenesis. J Pharmacol Exp Ther. 2015 Aug;354(2):142-51.
CAS Number: 1215281-19-8
Molecular Weight: 372.18
Compound Purity: 99.54
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Sirtuin