YKL-05-099, CAS 1936529-65-5

Product Description: YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM)[1].

Applications: COVID-19-immunoregulation

Formula: C32H34ClN7O3

References: [1]Sundberg TB, et al. Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo. ACS Chem Biol. 2016 Aug 19;11(8):2105-11.

CAS Number: 1936529-65-5

Molecular Weight: 600.11

Compound Purity: 99.76

Research Area: Inflammation/Immunology

Solubility: DMSO : ≥ 75 mg/mL

Target: Salt-inducible Kinase (SIK)

• SKU: MEXHY-101147-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101147-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK