YL-109, CAS 36341-25-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-(2-benzothiazolyl)-2-methoxy-phenol

Purity: ≥98%

Formula Markup: C14H11NO2S

Formula Weight: 257.30868

CAS Number: 36341-25-0

Notes: YL-109 is an anticancer agent.{52496} It inhibits the proliferation of MCF-7 and MDA-MB-231 cells (IC50s = 0.0858 and 4.2 µM, respectively), as well as migration and invasion by MDA-MB-231 cells in vitro. It induces expression of carboxyl terminus of Hsp70-interacting protein (CHIP) in MDA-MB-231 cells in an AHR-dependent manner. YL-109 (1 µM) inhibits MDA-MB-231-derived cancer stem cell (CSC) mammosphere formation. In vivo, YL-109 (15 mg/kg) reduces tumor volume and the number of metastases in an MDA-MB-231 mouse xenograft model.

• SKU: CAY30290-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 30290-50
• Package Unit: 50 mg
• Quantity Unit: STK