Product Description: Z16078526 induces endogenous Ucp1 expression, promotes p38 MAPK phosphorylation and lipolysis in primary mouse brown adipocytes. Z16078526 activates thermogenic gene expression and mitochondrial activity (uncoupled respiration) in mouse brown adipocytes. Z16078526 also stimulates thermogenesis in the mouse[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C18H17N3O4S
References: [1]Vergnes L, et al. Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation. J Biol Chem. 2020 Oct 30;295(44):15054-15069.
CAS Number: 852222-94-7
Molecular Weight: 371.41
Compound Purity: 98.13
Research Area: Others
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)