Product Description: Zamifenacin fumarate (UK-76654 fumarate) is a potent gut-selective muscarinic M3 receptor antagonist. Zamifenacin significantly reduces colonic motility in irritable bowel syndrome[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C31H33NO7
References: [1]Houghton LA, et al. Zamifenacin (UK-76, 654) a potent gut M3 selective muscarinic antagonist, reduces colonic motor activity in patients with irritable bowel syndrome. Aliment Pharmacol Ther. 1997 Jun;11(3):561-8./[2]Beaumont KC, et al. Pharmacokinetics and metabolism of Zamifenacin in mouse, rat, dog and man. Xenobiotica. 1996 Apr;26(4):459-71.
CAS Number: 127308-98-9
Molecular Weight: 531.60
Compound Purity: 99.0
Research Area: Metabolic Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 1 mg/mL (ultrasonic;warming;heat to 60°C)
Target: mAChR
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