Zidesamtinib, CAS 2739829-00-4

Product Description: Zidesamtinib (NVL-520) is a potent, selective, orally active and brain-penetrant inhibitor of diverse ROS1 fusions and resistance mutations, with IC50s of 0.7 and 7.9 nM for wild-type ROS1 and ROS1 G2032R, respectively, and spares TRK inhibition. Zidesamtinib can be used for the research of cancer[1].

Applications: Cancer-Kinase/protease

Formula: C22H22FN7O

References: [1]Drilon A, et, al. NVL-520 is a selective, TRK-sparing, and brain-penetrant inhibitor of ROS1 fusions and secondary resistance mutations. Cancer Discov. 2022 Dec 13;CD-22-0968.

CAS Number: 2739829-00-4

Molecular Weight: 419.45

Compound Purity: 99.55

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 65°C)

Target: ROS Kinase

• SKU: MEXHY-152292-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-152292-100
• Package Unit: 100 mg
• Quantity Unit: STK