Product Description: ZINC194100678 is a potent PAK1 inhibitor with an IC50 value of 8.37 μM. ZINC194100678 can inhibit MDA-MB-231 cell proliferation. ZINC194100678 can be used for researching anticancer[1].
Applications: Cancer-Kinase/protease
Formula: C10H13N5O
References: [1]Zhang J, et al. Design, synthesis and biological evaluation of 1H-pyrazolo [3,4-d]pyrimidine derivatives as PAK1 inhibitors that trigger apoptosis, ER stress and anti-migration effect in MDA-MB-231 cells. Eur J Med Chem. 2020;194:112220.
CAS Number: 1995025-05-2
Molecular Weight: 219.24
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: PAK