ZM 39923 (hydrochloride), CAS 1021868-92-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-1-propanone, monohydrochloride

Purity: ≥98%

Formula Markup: C23H25NO / HCl

Formula Weight: 367.9

CAS Number: 1021868-92-7

Notes: ZM 39923 is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 µM, respectively).{27341} In the absence of the reducing agent dithiothreitol, ZM 39923 also inhibits human tissue transglutaminase 2 (TGM2) and the transglutaminase Factor XIIIa (IC50s= 10 and 25 nM, respectively).{22726} It breaks down in neutral buffer to form ZM 449829, which is also an inhibitor of JAK3, TGM2, and Factor XIIIa.{27341,22726}

• SKU: CAY16729-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 16729-10
• Package Unit: 10 mg
• Quantity Unit: STK