ZM-447439, CAS 331771-20-1

Product Description: ZM-447439 is an aurora kinase inhibitor with IC50s of 110 and 130 nM for aurora A and B, respectively.

Applications: Cancer-Kinase/protease

Formula: C29H31N5O4

References: [1]Ditchfield C, et al. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol. 2003 Apr 28;161(2):267-80./[2]Long ZJ, et al. ZM 447439 inhibition of aurora kinase induces Hep2 cancer cell apoptosis in three-dimensionalculture. Cell Cycle. 2008 May 15;7(10):1473-9.

CAS Number: 331771-20-1

Molecular Weight: 513.59

Compound Purity: 99.19

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Apoptosis;Aurora Kinase

• SKU: MEXHY-10128-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10128-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK