2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate (sodium salt)

Formulation: A solution in water

Formal Name: 2' or 3′-(2-aminobenzoate)guanosine 5′-(tetrahydrogen triphosphate), tetrasodium salt

Purity: ≥95% (mixture of isomers)

Formula Markup: C17H17N6O15P3 • 4Na

Formula Weight: 730,2

Shelf life (days): 730

Notes: 2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate (2'-ANT-GTP) and 3'-ANT-GTP are fluorescent GTP derivatives, which undergo spontaneous isomerization.{65690} 2'(3')-ANT-GTP displays an emission maximum of 428 nm upon excitation at 330 nm in water.{67581} It inhibits mammalian adenylyl cyclase 1 (AC1; Ki = 10 nM in the presence of manganese), B. anthracis AC toxin edema factor (Kis = 4.1 and 13 µM in the presence of manganese and magnesium, respectively), and B. pertussis AC toxin CyaA (Ki = 29 µM in the presence of manganese).{65690,65692,65691}

• SKU: CAY38812-3.2
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38812-3.2
• Green Labware: No
• Package Unit: 3,2 mg
• Quantity Unit: STK