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Application: Study enzyme kinetics, and screen small molecular inhibitors of histone demethylases for HTS applications in drug discovery.
Description: The 4x HDM Assay Buffer 3 is optimized for use with the following BPSBioscience histone demethylase assay kits:/ JMJD2C (KDM4C) Homogeneous Assay Kit, BPS Cat. #50415/ JMJD2E (KDM4DL) Homogeneous Assay Kit, BPS Cat. #50417/ JMJD3 (KDM6B) Homogeneous Assay Kit, BPS Cat. #50416/ PHF8 (KDM7B) Homogeneous Assay Kit, BPS Cat. #50515
Format: Aqueous buffer solution
Storage Stability: Stable for at least 1 year when stored as directed.
Supplied As: HEPES-based buffer containing reducing agent
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)