Histone H4 Peptide (1-23), Monomethyl R3, Biotin-labeled

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Encompassing Amino Acids: 1-23

Amino Acid Sequence: SG-R(Me1)-GKGGKGLGKGGAKRHRKVLRGG-K(Biotin)

Application: Useful as a substrate for arginine methyltransferases and for screening small molecular inhibitors of Histone 4 (R3) methyltransferases for drug discovery.

Concentration: 200 µM

Description: This peptide is histone H4 (1-23) monomethylated at Arg3 followed by a biotinylated Lys conjugated to a C-terminal GG linker. Methylation of Arg3 is catalyzed by PRMT1 and functions to promote p300 acetylation of histone H4.

Purity: ≥95% by HPLC

Storage Stability: -20°C. Stable at least 1 year from date of receipt when stored as recommended.

Supplied As: 200 uM solution in water

Tags: Biotin labeled

Uniprot: P62805

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: Wang, H. et al. Science 293, 853 (2001).

• SKU: BPS51201
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 51201
• Package Unit: 40 nmole
• Quantity Unit: STK
• Host: Other