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Application: Study enzyme kinetics, and screen small molecular inhibitors of histone demethylases for HTS applications in drug discovery.
Description: The 4x HDM Assay Buffer 2 is optimized for use with the following BPS Bioscience histone demethylase assay kits: / JARID1A (KDM5A) Homogeneous Assay Kit, BPS Cat. #50510 / JARID1B (KDM5B) Homogeneous Assay Kit, BPS Cat. #50512 / JMJD1A (KDM3A) Homogeneous Assay Kit, BPS Cat. #50412 / JMJD2B (KDM4B) Homogeneous Assay Kit, BPS Cat. #50414
Format: Aqueous buffer solution
Storage Stability: Stable for at least 1 year when stored as directed.
Supplied As: HEPES-based buffer containing reducing agent
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)